BE2008C047I2 - - Google Patents
Download PDFInfo
- Publication number
- BE2008C047I2 BE2008C047I2 BE2008C047C BE2008C047C BE2008C047I2 BE 2008C047 I2 BE2008C047 I2 BE 2008C047I2 BE 2008C047 C BE2008C047 C BE 2008C047C BE 2008C047 C BE2008C047 C BE 2008C047C BE 2008C047 I2 BE2008C047 I2 BE 2008C047I2
- Authority
- BE
- Belgium
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Neurology (AREA)
- Materials Engineering (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99309558 | 1999-11-29 | ||
| PCT/EP2000/011789 WO2001040316A1 (en) | 1999-11-29 | 2000-11-23 | 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE2008C047I2 true BE2008C047I2 (en]) | 2019-12-11 |
Family
ID=8241767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE2008C047C BE2008C047I2 (en]) | 1999-11-29 | 2008-12-10 |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | USRE44733E1 (en]) |
| EP (1) | EP1259550B1 (en]) |
| JP (2) | JP3880041B2 (en]) |
| KR (1) | KR100716524B1 (en]) |
| CN (1) | CN1188428C (en]) |
| AR (1) | AR026605A1 (en]) |
| AT (1) | ATE288450T1 (en]) |
| AU (1) | AU776536B2 (en]) |
| BE (1) | BE2008C047I2 (en]) |
| BR (1) | BRPI0015947B8 (en]) |
| CA (1) | CA2390463C (en]) |
| CO (1) | CO5251450A1 (en]) |
| CY (1) | CY2008018I2 (en]) |
| CZ (1) | CZ298206B6 (en]) |
| DE (2) | DE122008000068I2 (en]) |
| DK (1) | DK1259550T3 (en]) |
| ES (1) | ES2237496T3 (en]) |
| FR (1) | FR08C0052I2 (en]) |
| HU (1) | HU227451B1 (en]) |
| IL (1) | IL149423A0 (en]) |
| LU (1) | LU91501I2 (en]) |
| MX (1) | MXPA02004940A (en]) |
| NL (1) | NL300356I2 (en]) |
| NO (2) | NO328790B1 (en]) |
| NZ (1) | NZ518752A (en]) |
| PE (1) | PE20010902A1 (en]) |
| PL (1) | PL203012B1 (en]) |
| PT (1) | PT1259550E (en]) |
| RU (1) | RU2260013C2 (en]) |
| SK (1) | SK286282B6 (en]) |
| TW (1) | TWI242015B (en]) |
| WO (1) | WO2001040316A1 (en]) |
| ZA (1) | ZA200203538B (en]) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6744471B1 (en) * | 1997-12-05 | 2004-06-01 | Olympus Optical Co., Ltd | Electronic camera that synthesizes two images taken under different exposures |
| TWI242015B (en) | 1999-11-29 | 2005-10-21 | Akzo Nobel Nv | 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
| EP1333842B1 (en) * | 2000-11-02 | 2006-08-30 | Akzo Nobel N.V. | Use of cortisol-sequestering agents for the treatment of hypercortisolaemia related disorders |
| CA2543443A1 (en) | 2003-10-31 | 2005-05-12 | The University Of Kansas | Sulfoalkyl ether-alkyl ether cyclodextrin derivatives |
| EP1735326A4 (en) | 2004-01-29 | 2011-04-20 | Pinnacle Pharmaceuticals | BETA-CYCLODEXTRIN DERIVATIVES AND THEIR USE AGAINST LETHAL ANTHRAX TOXIN |
| PT3520779T (pt) | 2004-04-23 | 2022-03-22 | Cydex Pharmaceuticals Inc | Formulação de dpi contendo éter sulfoalquílicociclodextrina |
| WO2006083678A2 (en) | 2005-01-28 | 2006-08-10 | Pinnacle Pharmaceuticals, Inc. | β-CYCLODEXTRIN DERIVATIVES AS ANTIBACTERIAL AGENTS |
| US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
| PL2952197T3 (pl) | 2005-10-26 | 2017-09-29 | Cydex Pharmaceuticals, Inc. | Kompozycje eteru sulfoalkilowego cyklodekstryny i sposoby ich wytwarzania |
| US20090069412A1 (en) * | 2007-09-09 | 2009-03-12 | Protia, Llc | Deuterium-enriched sugammadex |
| US7635773B2 (en) | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
| US7938283B2 (en) * | 2008-06-20 | 2011-05-10 | Grainpro, Inc. | System and method for hermetic storage of agricultural commodities during shipping |
| US10463677B2 (en) | 2008-11-07 | 2019-11-05 | Cydex Pharmaceuticals, Inc. | Composition containing sulfoalkyl ether cyclodextrin and latanoprost |
| CN101591402B (zh) * | 2009-05-05 | 2011-11-30 | 杭州奥默医药技术有限公司 | 6-脱氧砜类环糊精衍生物及其制备方法 |
| US8492538B1 (en) | 2009-06-04 | 2013-07-23 | Jose R. Matos | Cyclodextrin derivative salts |
| DE102010012281A1 (de) * | 2010-03-22 | 2011-09-22 | Fresenius Medical Care Deutschland Gmbh | Pharmazeutische Zusammensetzungen enthaltend substituiertes 6-Deoxy-6-sulfanylcyclodextrin |
| CN101864003B (zh) * | 2010-06-11 | 2012-05-02 | 漆又毛 | 一种6-脱氧硫醚氨基酸环糊精衍生物的合成方法 |
| PL2609120T3 (pl) * | 2010-08-25 | 2016-03-31 | Davuluri Ramamohan Rao | Ulepszony sposób wytwarzania sugammadeksu |
| CN102060941B (zh) | 2010-11-26 | 2012-12-26 | 漆又毛 | 6-脱氧α-氨基酸衍生物环糊精及制备和应用 |
| JP6508944B2 (ja) | 2012-02-15 | 2019-05-08 | サイデックス・ファーマシューティカルズ・インコーポレイテッド | シクロデキストリン誘導体のための製造方法 |
| CA2865950C (en) | 2012-02-28 | 2016-12-20 | Cydex Pharmaceuticals, Inc. | Alkylated cyclodextrin compositions and processes for preparing and using the same |
| JP5892847B2 (ja) * | 2012-04-27 | 2016-03-23 | Ｄｏｗａホールディングス株式会社 | シクロデキストリンとシリカ含有物質との複合材料、及びその製造方法、並びにガス吸着剤 |
| GB201211153D0 (en) * | 2012-06-22 | 2012-08-08 | Farmhispania | Pharmaceutical compositions |
| US10040872B2 (en) | 2012-10-22 | 2018-08-07 | Cydex Pharmaceuticals, Inc. | Alkylated cyclodextrin compositions and processes for preparing and using the same |
| US9879096B2 (en) * | 2013-02-14 | 2018-01-30 | Neuland Laboratories Limited | Process for preparation of sugammadex sodium |
| US10662260B2 (en) | 2014-05-29 | 2020-05-26 | Uti Limited Partnership | Cyclodextrin-based polyanionic and non-ionic dendrimers |
| JP5684954B1 (ja) | 2014-06-26 | 2015-03-18 | 丸石製薬株式会社 | 安定性を改善したロクロニウム製剤 |
| DK3183295T3 (da) | 2014-08-22 | 2023-08-21 | Cydex Pharmaceuticals Inc | Fraktioneret alkyleret cyclodextrinsammensætning og fremgangsmåder til fremstilling og anvendelse af samme |
| CN105348412B (zh) * | 2014-08-22 | 2018-06-05 | 江苏恩华药业股份有限公司 | 一种舒更葡糖钠的纯化方法 |
| CN108348560A (zh) | 2015-03-19 | 2018-07-31 | 锡德克斯药物公司 | 包含水飞蓟素和磺烃基醚环糊精的组合物及其使用方法 |
| CN104844732B (zh) * | 2015-03-27 | 2017-05-03 | 山东滨州智源生物科技有限公司 | 一种舒更葡糖钠的制备方法 |
| WO2016161501A1 (en) * | 2015-04-08 | 2016-10-13 | Ling Chang-Chun | Pharmaceutical compositions of polyanionic and non-ionic cyclodextrin-based dendrimers and uses thereof |
| CN107849157A (zh) * | 2015-05-29 | 2018-03-27 | 拉克什米·普拉萨德·阿拉帕斯 | 制备舒更葡糖及其中间体的方法 |
| CN104922693A (zh) * | 2015-06-19 | 2015-09-23 | 南开大学 | 一种阴离子型环糊精与抗癌药物包合物及制备方法 |
| JP2018530653A (ja) * | 2015-10-07 | 2018-10-18 | ユーティアイ リミテッド パートナーシップＵｔｉ Ｌｉｍｉｔｅｄ Ｐａｒｔｎｅｒｓｈｉｐ | 多官能性ポリアニオン性シクロデキストリンデンドリマー |
| EP3741801A1 (en) | 2015-11-25 | 2020-11-25 | Fresenius Kabi iPSUM S.r.l. | Crystalline forms of per-chloro-gamma-cyclodextrines |
| WO2017089966A1 (en) | 2015-11-25 | 2017-06-01 | Fresenius Kabi Antiinfectives S.R.L. | An improved process for the preparation of sugammadex and its intermediates |
| US10577433B2 (en) | 2016-03-22 | 2020-03-03 | Fresenius Kabi Ipsum S.R.L. | Process for the preparation of sugammadex |
| AU2017256640B2 (en) * | 2016-04-29 | 2020-07-30 | Alveron Pharma B.V. | Cyclodextrins as Procoagulants |
| EP3474865B1 (en) | 2016-06-23 | 2022-03-02 | Synthon BV | Process for making sugammadex |
| US20180016359A1 (en) | 2016-06-29 | 2018-01-18 | Beijing Creatron Institute Of Pharmaceutical Research Co., Ltd. | Sugammadex preparation and purification method |
| US10526422B2 (en) | 2016-06-29 | 2020-01-07 | Beijing Creatron Institute Of Pharmaceutical Research Co., Ltd. | Process for preparation and purification of Sugammades sodium |
| CN107778383B (zh) * | 2016-08-24 | 2020-03-10 | 王炳永 | 一种舒更葡糖钠的精制方法 |
| US10385142B2 (en) | 2017-01-23 | 2019-08-20 | Scinopharm Taiwan, Ltd. | Method for preparing sugammadex sodium |
| CN110831588B (zh) | 2017-05-03 | 2023-06-27 | 锡德克斯药物公司 | 包含环糊精和白消安的组合物 |
| CN109021148B (zh) * | 2017-06-08 | 2020-11-10 | 天津科伦药物研究有限公司 | 一种制备舒更葡糖钠的方法 |
| US10442871B2 (en) * | 2017-06-22 | 2019-10-15 | Lawrence Livermore National Security, Llc | Modified cyclodextrins for the selective sequestration of fentanyl related compounds and uses thereof |
| EP3421504B1 (en) | 2017-06-30 | 2019-09-18 | Synthon B.V. | Process for making sugammadex |
| US10233263B1 (en) * | 2017-08-23 | 2019-03-19 | Formosa Laboratories, Inc. | Method for preparation of sugammadex sodium |
| TWI703163B (zh) * | 2017-08-23 | 2020-09-01 | 台耀化學股份有限公司 | 舒更葡糖鈉之製備方法及其晶型 |
| US11104746B2 (en) | 2017-11-27 | 2021-08-31 | Medichem, S.A. | Process for the synthesis of a cyclodextrin derivative |
| CN107892727B (zh) * | 2017-11-27 | 2019-12-24 | 合肥博思科创医药科技有限公司 | 一种舒更葡糖钠的纯化方法 |
| EP4047047A1 (en) | 2018-04-06 | 2022-08-24 | Synthon B.V. | Purification of sugammadex |
| KR102054228B1 (ko) | 2018-05-28 | 2019-12-10 | 연성정밀화학(주) | 슈가마덱스 나트륨염의 제조방법 |
| JP7461304B2 (ja) * | 2018-06-07 | 2024-04-03 | メルク・シャープ・アンド・ドーム・エルエルシー | スガマデクスの製造方法 |
| CN110615860A (zh) * | 2018-06-20 | 2019-12-27 | 江苏恒瑞医药股份有限公司 | 一种舒更葡糖钠的纯化方法 |
| HRP20250729T1 (hr) * | 2018-08-02 | 2025-08-15 | Tapi Croatia Industries Ltd | Kruti oblici sugammadeks natrija |
| US11845811B2 (en) | 2018-09-20 | 2023-12-19 | Natco Pharma Limited | Process for the preparation of Sugammadex sodium and its novel polymorphic form |
| US20220049023A1 (en) | 2018-09-27 | 2022-02-17 | Werthenstein Biopharma Gmbh | Novel crystalline forms of sugammadex |
| JP6950966B2 (ja) * | 2018-11-01 | 2021-10-13 | 丸石製薬株式会社 | スガマデクス又はその薬理学的に許容される塩含有液剤及びその製造方法 |
| CN109438591B (zh) * | 2018-12-29 | 2021-02-09 | 博瑞生物医药（苏州）股份有限公司 | 舒更葡糖钠的制备工艺 |
| CN109824800A (zh) * | 2018-12-29 | 2019-05-31 | 鼎元(天津)生物医药科技有限公司 | 一种选择性肌松拮抗药舒更葡萄糖钠的制备方法 |
| US20220169753A1 (en) | 2019-03-29 | 2022-06-02 | Hospira, Inc. | An improved process for preparation of sugammadex acid and sugammadex sodium |
| CN111978435B (zh) | 2019-05-22 | 2021-05-25 | 合肥博思科创医药科技有限公司 | 一种高纯度舒更葡糖钠的制备方法 |
| US11324692B2 (en) | 2019-07-03 | 2022-05-10 | Galenicum Health S.L.U. | Method to prepare pharmaceutical compositions of suggamadex |
| JP7617844B2 (ja) | 2019-08-30 | 2025-01-20 | テルモ株式会社 | 注射液製剤 |
| RU2724900C1 (ru) * | 2019-10-24 | 2020-06-26 | Маруиси Фармасьютикал Ко., Лтд. | Препарат рокурония с улучшенной стабильностью |
| CN111019016B (zh) * | 2019-12-27 | 2022-02-18 | 武汉嘉诺康医药技术有限公司 | 一种舒更葡糖钠杂质的合成方法 |
| JP2023515087A (ja) | 2020-02-28 | 2023-04-12 | メディチェム エセ．ア． | スガマデクスを乾燥させるための方法 |
| CN111714459B (zh) * | 2020-06-18 | 2022-06-14 | 广州瑞尔医药科技有限公司 | 一种注射用舒更葡糖钠粉针剂及其制备方法 |
| US11097023B1 (en) | 2020-07-02 | 2021-08-24 | Par Pharmaceutical, Inc. | Pre-filled syringe containing sugammadex |
| ES2949710T1 (es) | 2020-07-03 | 2023-10-02 | Galenicum Health S L U | Método para preparar composiciones farmacéuticas |
| US11446325B2 (en) * | 2020-09-30 | 2022-09-20 | Cyclolab Cyclodextrin Research And Development Laboratory Ltd. | Cyclodextrin derivatives in the treatment or prevention of lysosomal neurodegenerative diseases |
| US11945788B2 (en) | 2021-06-07 | 2024-04-02 | Nuray Chemicals Private Limited | Process for preparing pitolisant hydrochloride and solid-state forms thereof |
| CN113637097A (zh) * | 2021-08-10 | 2021-11-12 | 北京恒创星远医药科技有限公司 | 6-全脱氧-6-全碘代-γ-环糊精晶体及其制备方法和应用 |
| CN120392546A (zh) | 2021-08-19 | 2025-08-01 | 北京费森尤斯卡比医药有限公司 | 包含巯基环糊精衍生物或其可药用盐的包装药品和保存方法 |
| CN119679816A (zh) * | 2023-09-15 | 2025-03-25 | 杭州奥默医药股份有限公司 | 一种用于逆转苄异喹啉类肌松药的肌松拮抗药物 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3929813A (en) * | 1973-12-26 | 1975-12-30 | Interx Research Corp | Novel pro-drug derivatives of pyridinium aldoxime type cholinesterase reactivators and process for preparing same |
| JPS52108027A (en) | 1976-03-09 | 1977-09-10 | Rikagaku Kenkyusho | Anticarcinogen |
| US4816462A (en) | 1982-05-18 | 1989-03-28 | Nowicky Wassili | Method for diagnosing and for the therapeutic treatment of tumors and/or infectious diseases of different types with alkaloid-compounds |
| HU194858B (en) | 1982-12-03 | 1988-03-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing dibenzo/b,d/pirane derivatives and pharmaceutical compositions containing them |
| IT1196033B (it) | 1984-02-22 | 1988-11-10 | Chiesi Farma Spa | Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche |
| US4727064A (en) | 1984-04-25 | 1988-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Pharmaceutical preparations containing cyclodextrin derivatives |
| GB8506792D0 (en) | 1985-03-15 | 1985-04-17 | Janssen Pharmaceutica Nv | Derivatives of y-cyclodextrin |
| GB8613688D0 (en) | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| JPH0819004B2 (ja) | 1986-12-26 | 1996-02-28 | 日清製粉株式会社 | 徐放性医薬製剤 |
| HU201783B (en) | 1987-10-13 | 1990-12-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing partially methylized carboxy-acyl-beta-cyclodextrines and salts |
| US5002935A (en) | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| US5017566A (en) | 1987-12-30 | 1991-05-21 | University Of Florida | Redox systems for brain-targeted drug delivery |
| US5173481A (en) | 1989-04-03 | 1992-12-22 | The United States Of America As Represented By The Department Of Health And Human Services | Preparation of specifically substituted cyclodextrins |
| ES2116982T3 (es) | 1989-04-03 | 1998-08-01 | Janssen Pharmaceutica Nv | Sustituciones regioselectivas en ciclodextrinas. |
| SU1703657A1 (ru) * | 1990-01-23 | 1992-01-07 | Пятигорский фармацевтический институт | Соединение включени диэтиламида никотиновой кислоты и @ -циклодекстрина, про вл ющее пролонгированное аналептическое действие |
| ES2067854T3 (es) * | 1990-03-15 | 1995-04-01 | Tanabe Seiyaku Co | Polisulfato de derivado de ciclodextrina y procedimiento para preparar el mismo. |
| US5180716A (en) * | 1990-08-01 | 1993-01-19 | The Regents Of The University Of California | Cyclodextrin complexes for neuraxial administration of drugs |
| US5180176A (en) * | 1991-08-08 | 1993-01-19 | Far Great Plastics Industrial Co., Ltd. | Elastic truck for roller skates |
| JP2556236B2 (ja) | 1991-08-29 | 1996-11-20 | 田辺製薬株式会社 | β−シクロデキストリン誘導体のポリ硫酸エステル及びその製法 |
| US5840881A (en) | 1992-11-27 | 1998-11-24 | Takeda Chemical Industries, Ltd. | Composition containing a water-insoluble or slightly water-soluble compound with enhanced water-solubility |
| US5767112A (en) | 1994-10-21 | 1998-06-16 | Poli Industria Chimica, S.P.A. | Muscle relaxant pharmaceutical compositions |
| AU708107B2 (en) | 1994-11-04 | 1999-07-29 | Commonwealth Scientific And Industrial Research Organisation | Method for treating animals |
| GB2307176A (en) * | 1995-11-15 | 1997-05-21 | Todd Selwyn Everest | Anti-inflammatory clathrating agents for topical use |
| US5935941A (en) | 1997-10-24 | 1999-08-10 | Pitha; Josef | Alkylations of cyclodextrins leading to derivatives which have a ridgidly extended cavity |
| US5834446A (en) * | 1996-06-21 | 1998-11-10 | Queen's University At Kingston | Nerve process growth modulators |
| JP4249282B2 (ja) | 1998-02-27 | 2009-04-02 | 日本食品化工株式会社 | 新規シクロデキストリン誘導体及びその製造方法 |
| EP1082292B1 (en) | 1998-05-29 | 2005-09-28 | Neurosciences Research Foundation | Control of pain with endogenous cannabinoids |
| IL147887A0 (en) | 1999-08-13 | 2002-08-14 | Akzo Nobel Nv | Use of chemical chelators as reversal agents for drug-induced neuromuscular block |
| TWI242015B (en) | 1999-11-29 | 2005-10-21 | Akzo Nobel Nv | 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
| US20020111377A1 (en) | 2000-12-22 | 2002-08-15 | Albany College Of Pharmacy | Transdermal delivery of cannabinoids |
| ATE325135T1 (de) | 2001-02-14 | 2006-06-15 | Akzo Nobel Nv | 2-alkylierte cyclodextrinderivate : umkehrungsmittel von medikament-induzierter neuromuskulärer blockierung |
| TW200402417A (en) | 2002-06-21 | 2004-02-16 | Akzo Nobel Nv | 1-[(Indol-3-yl)carbonyl]piperazine derivatives |
-
2000
- 2000-11-08 TW TW089123585A patent/TWI242015B/zh not_active IP Right Cessation
- 2000-11-23 PL PL356097A patent/PL203012B1/pl unknown
- 2000-11-23 ES ES00993261T patent/ES2237496T3/es not_active Expired - Lifetime
- 2000-11-23 SK SK726-2002A patent/SK286282B6/sk not_active IP Right Cessation
- 2000-11-23 AU AU54380/01A patent/AU776536B2/en not_active Expired
- 2000-11-23 IL IL14942300A patent/IL149423A0/xx active Protection Beyond IP Right Term
- 2000-11-23 MX MXPA02004940A patent/MXPA02004940A/es active IP Right Grant
- 2000-11-23 CZ CZ20021814A patent/CZ298206B6/cs not_active IP Right Cessation
- 2000-11-23 CN CNB00816360XA patent/CN1188428C/zh not_active Expired - Lifetime
- 2000-11-23 NZ NZ518752A patent/NZ518752A/xx not_active IP Right Cessation
- 2000-11-23 KR KR1020027006871A patent/KR100716524B1/ko not_active Expired - Lifetime
- 2000-11-23 US US13/432,742 patent/USRE44733E1/en active Active
- 2000-11-23 BR BRPI0015947 patent/BRPI0015947B8/pt not_active IP Right Cessation
- 2000-11-23 AT AT00993261T patent/ATE288450T1/de active
- 2000-11-23 PT PT00993261T patent/PT1259550E/pt unknown
- 2000-11-23 RU RU2002117302/04A patent/RU2260013C2/ru active Protection Beyond IP Right Term
- 2000-11-23 HU HU0203755A patent/HU227451B1/hu active Protection Beyond IP Right Term
- 2000-11-23 US US10/148,307 patent/US6670340B1/en not_active Ceased
- 2000-11-23 CA CA002390463A patent/CA2390463C/en not_active Expired - Lifetime
- 2000-11-23 DE DE122008000068C patent/DE122008000068I2/de active Active
- 2000-11-23 JP JP2001541070A patent/JP3880041B2/ja not_active Expired - Lifetime
- 2000-11-23 EP EP00993261A patent/EP1259550B1/en not_active Expired - Lifetime
- 2000-11-23 DK DK00993261T patent/DK1259550T3/da active
- 2000-11-23 WO PCT/EP2000/011789 patent/WO2001040316A1/en active IP Right Grant
- 2000-11-23 DE DE60017947T patent/DE60017947T2/de not_active Expired - Lifetime
- 2000-11-27 AR ARP000106216A patent/AR026605A1/es active IP Right Grant
- 2000-11-28 CO CO00090982A patent/CO5251450A1/es active IP Right Grant
- 2000-11-28 PE PE2000001269A patent/PE20010902A1/es not_active IP Right Cessation
-
2002
- 2002-05-03 ZA ZA200203538A patent/ZA200203538B/en unknown
- 2002-05-28 NO NO20022522A patent/NO328790B1/no not_active IP Right Cessation
-
2003
- 2003-06-23 US US10/603,355 patent/US6949527B2/en not_active Expired - Lifetime
-
2006
- 2006-07-18 JP JP2006195089A patent/JP4563972B2/ja not_active Expired - Lifetime
-
2008
- 2008-08-06 NL NL300356C patent/NL300356I2/nl unknown
- 2008-11-25 CY CY200800018C patent/CY2008018I2/el unknown
- 2008-11-26 LU LU91501C patent/LU91501I2/xx unknown
- 2008-12-10 BE BE2008C047C patent/BE2008C047I2/fr unknown
- 2008-12-30 FR FR08C0052C patent/FR08C0052I2/fr active Active
-
2010
- 2010-11-10 NO NO2010019C patent/NO2010019I2/no unknown